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Capsule affects pneumococcal resistance do indolicidin. Wild-type pneumococcal strains D39 (serotype 2) and TIGR4 (serotype 4) and their capsule-negative mutants AM1001 (D39 background) and HR1001 (TIGR background) were treated with indolicidin at 15 μg/ml (A) and 30 μg/ml (B) and plated. The percent reduction in bacterial survival is shown for each group. Statistical analysis was performed using Student’s t-test. *p < 0.05 in comparison with the wild-type strain; ns, not significant.
