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. 2022 May 13;13:898815. doi: 10.3389/fmicb.2022.898815

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Copyright © 2022 Waz, Oliveira, Girardello, Lincopan, Barazzone, Parisotto, Hakansson, Converso and Darrieux.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of free capsular polysaccharide on the lytic action of indolicidin. Peumococcal strains St 245/00 (A), St 0603, serotype 6B (B), D39, serotype 2 and its capsule-negative mutant (C), and TIGR4 and its capsule-negative mutant (D) were treated with indolicidin preincubated with purified CPS 6B. Each bar represents the percent in survival relative to the control group. Statistical analysis was performed using Student’s t-test. ^*p < 0.05 in comparison with indolicidin treatment in absence of CPS. ns, not significant.