. 2021 Dec 24;12(5):2417–2428. doi: 10.1016/j.apsb.2021.12.013

Table 1.

Binding affinity (EC₅₀, nmol/L) of glycoengineered trastuzumab with various Fc receptors.

Entry	mAb	CD16a (V176)	CD32a (H167)	CD64	FcRn
1	Tras	92.04	301.7	12.02	11.48
2	1a	3342	7946	75.08	24.3
3	1b	441.4	9797	57.67	20.91
4	6a	635.5	2014	40.03	13.48
5	6c	691.6	1996	36.14	14.59
6	7a	68.47	1829	32.57	17.41
7	7c	65.2	1972	29.65	15.68
8	S2G2(F)-Tras	81.69	132.4	10.78	5.149
9	S2G2-Tras	15.45	135.8	9.612	20.73