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. 2022 Apr 26;21:101435. doi: 10.1016/j.tranon.2022.101435

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© 2022 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 3 — DEGs analysis and the key gene selection (A) Volcano plot of DEGs in the GSE49355; (B) Volcano plot of DEGs in the GSE81582; (C) The Venn diagram of genes among DEGs and co-expression modules; (D) The forest plot of univariate Cox proportional hazard analysis and 4 genes were considered as candidate genes associated with prognosis; (E-H) OS analysis for HSD11B2, IMPA2, PIGR, and PXMP2 in the GEPIA2 database. (I-L) DFS analysis for HSD11B2, IMPA2, PIGR, and PXMP2 in the GEPIA2 database. Abbreviations: DEG, differentially expressed genes; OS, overall survival; DFS, diseases-free survival; GEPIA2, Gene Expression Profiling Interactive Analysis 2; HSD11B2, hydroxysteroid 11-beta dehydrogenase 2; IMPA2, inositol Mono-phosphatase 2; PIGR, polymeric immunoglobulin receptor; PXMP2, peroxisomal membrane protein 2; HR, hazard ratio; CI, confidence interval.