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In vivo anti-metastasis of NGP@MI. (A) Schematic illustration of the anti-metastasis experiment. (B) Images of fresh lung tissue and Bouin's fixed lung tissue. Pulmonary metastasis nodules (C) and lung weight (D) of 4T1 tumor bearing mice which treated with saline, PTX, IL-2, PTX + IL-2 and NG@M, NGP@M, NG@MI, NGP@MI (n = 9). (E) HE images of lung tissues. Statistical P values: ∗∗P < 0.01, ∗∗∗P < 0.001, scale bar = 2.5 mm (above) and 500 μm (below).
