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Blood pharmacokinetic profiles of DOX-loaded mPEG-PCL nanoparticle in rats as highlighted by comparing PEGylation density (A), PEG chain length (B) and particle size (C), respectively. Plot D, E & F are enlargement of the 0–4 h regions of plot A, B and C, respectively, while bar plot G, H & I present corresponding AUC values as summarized in Table 2, Table 3. Data are presented as mean ± SD (n = 3).
