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. 2021 Nov 18;12(5):2479–2493. doi: 10.1016/j.apsb.2021.11.016

Table 1.

Characterization of DOX-loaded mPEG-PCL nanoparticlesa.

Parameter PCL-80 nm mPEG5k-9%-80 nm mPEG5k-17%-80 nm mPEG5k-29%-80 nm mPEG2k-29%-80 nm mPEG5k-29%-200 nm
Particle size (nm) 81.7 ± 0.9 82.5 ± 1.1 83.2 ± 1.8 86.2 ± 0.6 85.3 ± 0.9 211.5 ± 2.8
PDI 0.104 ± 0.010 0.113 ± 0.008 0.115 ± 0.010 0.108 ± 0.008 0.112 ± 0.008 0.102 ± 0.005
Zeta-potential (mV) ‒1.22 ± 0.04 ‒1.25 ± 0.11 ‒1.27 ± 0.09 ‒1.33 ± 0.10 ‒1.24 ± 0.04 ‒1.28 ± 0.07
Entrapment efficiency (%) 22.43 ± 0.82 20.74 ± 0.5 21.49 ± 1.59 22.97 ± 1.39 21.69 ± 1.55 36.47 ± 1.56
Drug loading (%) 0.87 ± 0.03 0.79 ± 0.01 0.73 ± 0.03 0.62 ± 0.03 0.62 ± 0.02 0.62 ± 0.02
Fluorescence intensity (×109) 5.31 ± 0.15 5.17 ± 0.09 5.58 ± 0.22 5.10 ± 0.18 5.29 ± 0.13 5.31 ± 0.18
a

Data are presented as mean ± SD (n = 3).