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. 2022 May 26;5(5):e2214153. doi: 10.1001/jamanetworkopen.2022.14153

Table 2. Inverse Probability of Treatment–Weighted 30-Day All-Cause Health Care Utilization and Total Per-Patient Expenditure Estimates of Inappropriate Antibiotic Prescriptions Among Children by Setting.

Expenditure category Health care utilization, No. (%) Total per-patient expenditure estimates, mean (SD), $
Appropriate antibiotic Inappropriate antibiotic Appropriate antibiotic Inappropriate antibiotic
Bacterial infections (primary analysis)
Suppurative OM
Total 402 815 (100.0) 181 486 (100.0) 426 (1985) 498 (2362)
Inpatient medical 954 (0.2) 449 (0.2) 42 (1639) 44 (1869)
Emergency department 10 743 (2.7) 49,12 (2.7) 34 (354) 36 (351)
Outpatient medical 401 128 (99.6) 180 777 (99.6) 300 (815) 315 (988)
Outpatient pharmacy 402 810 (100.0) 181 486 (100.0) 50 (501) 103 (678)
Pharyngitis
Total 398 702 (100.0) 203 231 (100.0) 392 (2164) 471 (2439)
Inpatient medical 913 (0.2) 477 (0.2) 44 (1837) 50 (2085)
Emergency department 9093 (2.3) 4926 (2.4) 32 (397) 41 (388)
Outpatient medical 397 324 (99.7) 202 460 (99.6) 265 (793) 290 (795)
Outpatient pharmacy 398 697 (100.0) 203 230 (100.0) 51 (539) 90 (639)
Sinusitis
Total 238 337 (100.0) 133 133 (100.0) 476 (2409) 507 (2684)
Inpatient medical 584 (0.2) 335 (0.3) 53 (1975) 49 (2013)
Emergency department 5217 (2.2) 2956 (2.2) 38 (392) 39 (429)
Outpatient medical 237 976 (99.8) 132 917 (99.8) 307 (997) 311 (1372)
Outpatient pharmacy 238 330 (100.0) 133 131 (100.0) 78 (669) 109 (704)
Viral infections (secondary analysis)
Influenza
Total 162 779 (100.0) 6366 (100.0) 549 (2254) 644 (1935)
Inpatient medical 382 (0.2) 11 (0.2) 43 (1989) 43 (1537)
Emergency department 8237 (5.1) 324 (5.1) 78 (492) 47 (411)
Outpatient medical 159 233 (97.8) 6201 (97.4) 270 (639) 341 (715)
Outpatient pharmacy 115 157 (70.7) 6366 (100.0) 158 (527) 213 (556)
Viral URI
Total 630 381 (100.0) 87 985 (100.0) 480 (2605) 531 (4251)
Inpatient medical 1546 (0.2) 267 (0.3) 53 (2239) 74 (3976)
Emergency department 22 367 (3.5) 2947 (3.3) 56 (463) 42 (437)
Outpatient medical 624 443 (99.1) 87 103 (99.0) 310 (946) 322 (1039)
Outpatient pharmacy 252 277 (40.0) 87 981 (100.0) 61 (589) 93 (817)
Bronchiolitis
Total 19 222 (100.0) 1994 (100.0) 783 (2362) 704 (1506)
Inpatient medical 214 (1.1) 13 (0.6) 147 (1967) 64 (1039)
Emergency department 1367 (7.1) 136 (6.8) 114 (529) 74 (515)
Outpatient medical 19 006 (98.9) 1970 (98.8) 476 (1002) 481 (817)
Outpatient pharmacy 10 119 (52.6) 1994 (100.0) 45 (360) 85 (358)
Bronchitis
Total 20 886 (100.0) 49 378 (100.0) 651 (2327) 515 (2406)
Inpatient medical 52 (0.2) 120 (0.2) 59 (1786) 57 (1968)
Emergency department 1022 (4.9) 2312 (4.7) 177 (837) 47 (456)
Outpatient medical 20 491 (98.1) 48 350 (97.9) 331 (1007) 299 (932)
Outpatient pharmacy 11 521 (55.2) 49 375 (100.0) 83 (374) 112 (719)
Nonsuppurative OM
Total 61 563 (100.0) 62 160 (100.0) 643 (2231) 480 (1989)
Inpatient medical 143 (0.2) 155 (0.2) 46 (1449) 41 (1508)
Emergency department 2106 (3.4) 2227 (3.6) 55 (438) 38 (384)
Outpatient medical 61 036 (99.1) 61 528 (99.0) 495 (1436) 334 (821)
Outpatient pharmacy 20 426 (33.2) 62 158 (100.0) 47 (506) 66 (634)

Abbreviations: OM, otitis media; URI, upper respiratory infection.