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Shifts in enteric bacterial composition after 6 months of intervention. (a, b) Numbers of species and Chao1 diversity indices of intestinal bacteria assessed by 16S rRNA high-throughput sequencing significant differ (Kruskal–Wallis χ2 test; n = 20 per group). (c, d) PCoA and NMDS analyses of intestinal bacterial composition profiles. NMDS: nonmetric multidimensional; PCoA: principal coordinate analysis.
