Table 1. Demographic and Clinical Characteristics of the Participants.
| Characteristic | All (N = 430) | Dropout group (n = 215) | No. (%), follow-up group (n = 215) | |
|---|---|---|---|---|
| Baseline | Follow-up | |||
| Age, mean (SD), y | 76.3 (6.6) | 76.2 (6.5) | 76.5 (6.7) | 80.9 (6.5) |
| Sex, No. (%) | ||||
| Women | 208 (48.6) | 102 (47.9) | 106 (49.3) | NA |
| Men | 222 (51.4) | 113 (52.1) | 50.7 (109) | NA |
| Education, mean (SD), y | 9.1 (5.6) | 9.2 (5.9) | 9.4 (5.7) | NA |
| Axial length, mean (SD), mm | 23.4 (1.2) | 23.5 (1.4) | 23.1 (1.3) | NA |
| IOP, mean (SD), mm Hg | 12.1 (3.3) | 11.9 (3.5) | 12.6 (3.1) | NA |
| APOE ε4, No. (%) | 70 (16.2) | 30 (14.0) | 40 (22.8) | NA |
| Diabetes, No. (%) | 90 (20.1) | 48 (22.3) | 42 (19.5) | NA |
| Hypertension, No. (%) | 170 (29.5) | 80 (37.2) | 90 (41.9) | NA |
| CERAD total score, mean (SD) | 66.7 (12.1) | 66.0 (16.5) | 66.6 (11.2) | 54.1 (11.4) |
| MMSE score, mean (SD) | 24.5 (4.6) | 24.4 (5.1) | 25.2 (3.2) | 21.5 (3.1) |
| Cognitive disorders, No. (%) | ||||
| MCI | 63 (14.7) | 38 (17.7) | 25 (11.6) | 38 (17.7) |
| Alzheimer disease | 12 (2.8) | 6 (2.8) | 6 (2.8) | 9 (4.2) |
| All | 75 (17.5) | 44 (20.4) | 31 (14.4) | 47 (21.9) |
Abbreviations: APOE, apolipoprotein E; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease Neuropsychological Battery; IOP, intraocular pressure; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination.