Table 3. Association of Baseline Macular Retinal Nerve Fiber Layer Thickness With Changes in Cognitive Performance During the Follow-up Perioda.
| Characteristic | CERAD total score | MMSE | ||
|---|---|---|---|---|
| F 208 | P value | F 208 | P value | |
| Outer | ||||
| Thickness | 1.170 | .21 | 0.956 | .56 |
| Lowest quartile (135 μm) | 6.912 | .01 | 4.265 | .04 |
| Inner | ||||
| Thickness | 1.229 | .16 | 1.358 | .09 |
| Lowest quartile (86 μm) | 7.600 | .006 | 6.626 | .01 |
| Total | ||||
| Thickness | 1.420 | .07 | 0.879 | .74 |
| Lowest quartile (231 μm) | 8.980 | .003 | 6.645 | .01 |
Abbreviations: CERAD, Consortium to Establish a Registry for Alzheimer’s Disease Neuropsychological Battery; MMSE, Mini-Mental State Examination.
a
Repeated-measures analysis of variance.