Table 4.
Stepwise logistic regression using backward selection
| Models and Variables | Full Model | Final Model | ||||||
|---|---|---|---|---|---|---|---|---|
| Odds Ratio | Standard Error | P Value | 95% Confidence Interval | Odds Ratio | Standard Error | P Value | 95% Confidence Interval | |
| Age, yr | 0.965 | 0.009 | 0.000 | 0.948 to 0.984 | 0.965 | 0.009 | 0.000 | 0.948 to 0.983 |
| Baseline CKD | 1.384 | 0.238 | 0.058 | 0.989 to 1.935 | 1.687 | 0.302 | 0.004 | 1.187 to 2.396 |
| Baseline COPD | 0.161 | 0.058 | 0.000 | 0.080 to 0.326 | 0.146 | 0.054 | 0.000 | 0.071 to 0.300 |
| Admission SOFA score | 1.140 | 0.415 | 0.001 | 1.058 to 1.229 | 1.225 | 0.046 | 0.000 | 1.137 to 1.319 |
| SOFA score within 24 hours of RRT start | 0.689 | 0.031 | 0.000 | 0.631 to 0.753 | 0.653 | 0.030 | 0.000 | 0.597 to 0.715 |
| Refractory hyperkalemia as indication | 3.512 | 1.026 | 0.000 | 1.982 to 6.225 | 3.763 | 1.103 | 0.000 | 2.118 to 6.685 |
| Uremic encephalopathy as indication | 0.558 | 0.156 | 0.037 | 0.322 to 0.965 | 0.317 | 0.077 | 0.000 | 0.197 to 0.510 |
| BUN >100 mg/dl at start | 1.495 | 0.415 | 0.148 | 0.867 to 2.577 | 1.855 | 0.503 | 0.023 | 1.090 to 3.152 |
| S. creatinine mg/dl at start | 1.151 | 0.070 | 0.021 | 1.021 to 1.297 | 1.206 | 0.077 | 0.003 | 1.065 to 1.366 |
| S. albumin >3.5 g/dl at start | 2.284 | 1.053 | 0.073 | 0.925 to 5.639 | 3.289 | 1.472 | 0.008 | 1.368 to 7.907 |
| CRRT chosen as initial RRT modality | 0.450 | 0.136 | 0.011 | 0.293 to 0.853 | 0.514 | 0.141 | 0.015 | 0.301 to 0.879 |
| Lactate at start, mmol/L | 0.809 | 0.039 | 0.000 | 0.737 to 0.889 | 0.805 | 0.037 | 0.000 | 0.735 to 0.882 |
| Severe volume overload at start | 1.657 | 0.424 | 0.048 | 1.004 to 2.735 | 1.440 | 0.362 | 0.148 | 0.879 to 2.358 |
| ICU after abdominal surgery | 3.870 | 2.161 | 0.015 | 1.296 to 11.562 | 3.766 | 2.128 | 0.019 | 1.244 to 11.396 |
| ICU after cardiac surgery | 1.156 | 0.334 | 0.617 | 0.655 to 2.038 | — | — | — | — |
| Active hematologic malignancy | 0.434 | 0.350 | 0.301 | 0.090 to 2.107 | — | — | — | — |
| Severe acidosis at start | 1.217 | 0.481 | 0.620 | 0.561 to 2.639 | — | — | — | — |
| On LVAD at start | 1.516 | 0.588 | 0.284 | 0.708 to 3.242 | — | — | — | — |
| On IABP at start | 1.215 | 0.509 | 0.643 | 0.534 to 2.761 | — | — | — | — |
| Constant | 155.413 | 131.238 | 0.000 | 29.696 to 813.353 | 123.778 | 100.556 | 0.000 | 25.185 to 608.344 |
| LR chi2 | 439.45 | 576.54 | ||||||
| Prob >chi2 | 0.0000 | 0.0000 | ||||||
| Pseudo R2 | 0.4565 | 0.5094 | ||||||
COPD, chronic obstructive pulmonary disease; SOFA, sequential organ failure assessment score; S., serum; CRRT, continuous RRT; ICU, intensive care unit; LVAD, left ventricular assist device; IABP, intra-aortic balloon pump; LR, likelihood ratio.