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. 2022 May 26;13:219. doi: 10.1186/s13287-022-02902-3

Fig. 6.

Fig. 6

Validation of a high-throughput organoid imaging assay by testing the chemosensitivity of tumor organoids. A Presentation of organoids that are sensitive or resistant to 5-FU (10 μM). D0 refers to the day of drug treatment and d10 means the tenth days post-d0. B, C The survival rate and total area of tumor organoids on day 10 after 5-FU treatment. The d0 count was set as the standard. A total of 176 organoids were measured in the 5-FU-sensitive group and 150 organoids were measured in the 5-FU-resistant group. D Presentation of organoids that are sensitive or resistant to CPT11 (10 μM). E, F The survival rate and total area of tumor organoids on day 10 after CPT-11 treatment. A total of 188 organoids were measured in the CPT-11-sensitive group, and 180 organoids were measured in the CPT-11-resistant group. Data are presented as the mean ± SD