Table 2.

Comparison relative abundance (permyriad) of microbiota among clinical informations

1. Sex		Female		Male
		mean	sd	mean	sd	p (Wilcox test)	Cliff’s delta	CI95
	Escherichia.Shigella	602.3	1176.4	465.6	1303.6	0.007	0.208	(0.06–0.34)
	Streptococcus	188.5	407.7	154.3	376.3	0.030	0.165	(0.02–0.30)
2. Age		≧70		< 70
		mean	sd	mean	sd	p (Wilcox test)	Cliff’s delta	CI95
	Sphingomonas	2.0	6.3	1.1	5.2	0.011	0.113	(0.03–0.20)
	Fusobacterium	319.5	717.4	420.6	705.5	0.044	−0.144	(−0.28–0.00)
3. progress
	a. in BDAC	Early		Advance
		mean	sd	mean	sd	p (Wilcox test)	Cliff’s delta	CI95
	Campylobacter	8.3	36.9	32.5	86.7	0.025	−0.212	(− 0.40 - -0.01)
	Citrobacter	57.9	392.1	93.0	226.3	0.001	−0.307	(− 0.49 - -0.10)
	Leptotrichia	0.0	0.4	41.2	194.6	0.007	−0.148	(− 0.21 - -0.09)
	b. in PDAC	Early		Advance
		mean	sd	mean	sd	p (Wilcox test)	Cliff’s delta	CI95
	Enterobacter	896.3	899.5	518.5	959.1	0.004	0.368	(0.13–0.56)
	Hungatella	97.0	526.4	5.9	38.5	0.007	0.232	(0.06–0.39)
	Mycobacterium	12.2	26.3	4.3	15.7	0.018	0.231	(0.03–0.41)
	Phyllobacterium	845.6	1307.8	1514.4	1560.3	0.023	−0.286	(−0.50 - -0.04)
	Sphingomonas	1.0	4.7	3.2	8.5	0.058	−0.164	(−0.32–0.00)
	c. in pancreas cystic lesion	IPMN		IPMC
		mean	sd	mean	sd	p (Wilcox test)	Cliff’s delta	CI95
	Actinomyces	0.3	1.1	4.6	7.0	0.038	−0.335	(−0.59 - -0.02)
	Alloprevotella	0.0	0.0	2.8	6.0	0.047	−0.200	(− 0.31 - -0.08)
	Bilophila	0.0	0.0	35.3	75.9	0.047	−0.200	(−0.31 - -0.08)
	Dialister	0.0	0.0	4.6	10.1	0.047	−0.200	(− 0.31 - -0.08)
	Eggerthella	0.0	0.0	26.6	56.6	0.047	−0.200	(−0.31 - -0.08)
	Selenomonas	0.0	0.0	0.9	2.0	0.047	−0.200	(− 0.31 - -0.08)
	Streptococcus	58.5	132.8	551.3	959.4	0.009	−0.600	(−0.86 - -0.09)

Early, without Lymphnode metastasis; Advanced, with Lymphnode metastasis; IPMN Intraductal papillary mucinous neoplasm, IPMC Intraductal papillary mucinous carcinoma, SD Standard deviation, BDAC Cholangiocarcinoma, PDAC Pancreatic ductal adenocarcinoma