Table 5.

Moderator effect of obesity on the relationship between menarche age and blood pressure in women (N=4513)

Dependent	Variables	Model 1*			Model 2†			Model 3‡			Model 4§			Model 5¶
		SE	B (95% CI)	P value	SE	B (95% CI)	P value	SE	B (95% CI)	P value	SE	B (95% CI)	P value	SE	B (95% CI)	P value
DBP	Menarche age	0.0835	−0.2027 (−0.3665 to −0.0390)	0.0153	0.0855	−0.2528 (−0.4203 to −0.0852)	0.0031	0.0853	−0.2411 (−0.4084 to −0.0738)	0.0047	0.0854	−0.2485 (−0.4158 to −0.0811)	0.0036	0.0973	−0.2162 (−0.4069 to −0.0254)	0.0263
	BMI	0.0440	0.6546 (0.5684 to 0.7409)	<0.001	0.0447	0.6757 (0.5881 to 0.7634)	<0.001	0.0449	0.6835 (0.5955 to 0.7715)	<0.001	0.0458	0.6647 (0.5750 to 0.7544)	<0.001	0.0556	0.5916 (0.4827 to 0.7005)	<0.001
	BMI×menarche age	0.0204	0.0279 (−0.0121 to 0.0678)	0.1719	0.0204	0.0258 (−0.0141 to 0.0658)	0.2046	0.0203	0.0247 (−0.0152 to 0.0645)	0.2248	0.0203	0.0220 (−0.0178 to 0.0618)	0.2790	0.0229	0.0260 (−0.0189 to 0.071)	0.2556
SBP	Menarche age	0.1826	−0.0003 (−0.3583 to 0.3576)	0.9986	0.1789	−0.5822 (−0.9329 to −0.2315)	0.0011	0.1788	−0.5682 (−0.9187 to −0.2177)	0.0015	0.1795	−0.5944 (−0.9462 to −0.2425)	<0.001	0.2141	−0.5084 (−0.9282 to −0.0886)	0.0176
	BMI	0.0964	0.8361 (0.6470 to 1.0251)	<0.001	0.0938	1.0927 (0.9088 to 1.2766)	<0.001	0.0942	1.0906 (0.9058 to 1.2753)	<0.001	0.0965	1.0287 (0.8396 to 1.2178)	<0.001	0.1223	0.8846 (0.6448 to 1.1244)	<0.001
	BMI×menarche age	0.0446	0.0178 (−0.0696 to 0.1052)	0.6896	0.0426	0.0111 (−0.0726 to 0.0947)	0.7955	0.0426	0.0113 (−0.0722 to 0.0948)	0.7914	0.0427	0.0052 (−0.0786 to 0.0889)	0.9038	0.0504	0.0091 (−0.0897 to 0.108)	0.8561
DBP	Menarche age	0.0838	−0.2569 (−0.4213 to −0.0925)	0.0022	0.0861	−0.2588 (−0.4277 to −0.0900)	0.0027	0.0861	−0.2481 (−0.4168 to −0.0794)	0.0040	0.0861	−0.2561 (−0.4248 to −0.0873)	0.0029	0.0979	−0.2001 (−0.3921 to −0.0082)	0.0410
	WC	0.0142	0.1732 (0.1452 to 0.2011)	<0.001	0.0143	0.1752 (0.1471 to 0.2032)	<0.001	0.0143	0.1730 (0.1449 to 0.2011)	<0.001	0.0145	0.1645 (0.1361 to 0.193)	<0.001	0.0172	0.1472 (0.1135 to 0.1809)	<0.001
	WC×menarche age	0.0065	0.0058 (−0.007 to 0.0186)	0.3758	0.0066	0.0054 (−0.0075 to 0.0182)	0.4136	0.0065	0.005 (−0.0079 to 0.0178)	0.4473	0.0065	0.0043 (−0.0085 to 0.0171)	0.5075	0.0074	0.0099 (−0.0047 to 0.0244)	0.1833
SBP	Menarche age	0.1777	−0.0009 (−0.3492 to 0.3475)	0.9961	0.1761	−0.5656 (−0.9107 to −0.2204)	0.0013	0.1760	−0.5546 (−0.8997 to −0.2094)	0.0016	0.1766	−0.581 (−0.9273 to −0.2347)	0.0010	0.2096	−0.4548 (−0.8658 to −0.0438)	0.0301
	WC	0.0302	0.3637 (0.3044 to 0.4229)	<0.001	0.0293	0.3228 (0.2654 to 0.3802)	<0.001	0.0294	0.3153 (0.2578 to 0.3729)	<0.001	0.0298	0.2944 (0.236 to 0.3528)	<0.001	0.0368	0.2744 (0.2022 to 0.3466)	<0.001
	WC×mtenarche age	0.0139	−0.0156 (−0.0428 to 0.0116)	0.2607	0.0134	−0.0061 (−0.0323 to 0.0202)	0.6501	0.0134	−0.0063 (−0.0326 to 0.0199)	0.6367	0.0134	−0.0081 (−0.0344 to 0.0182)	0.5443	0.0159	−0.0032 (−0.0343 to 0.028)	0.8427

*Unadjusted.

†Adjusted for age, educational attainment, marital status and region.

‡Adjusted for age, educational attainment, marital status, region, smoking status, alcohol consumption, eating habits, entertainment, experience of a traumatic event and physical activity.

§Adjusted for age, educational attainment, marital status, region, smoking status, alcohol consumption, eating habits, entertainment, experience of a traumatic event, physical activity, history of CVDs, hepatitis history, antihyperlipidaemic drugs and antidiabetic drugs.

¶ Adjusted for age, educational attainment, marital status, region, smoking status, alcohol consumption, eating habits, entertainment, experience of a traumatic event, physical activity, history of CVDs, hepatitis history, antihyperlipidaemic drugs, antidiabetic drugs, LDL-C, HDL-C, TG, HbA1c, Scr and SUA.

BMI, body mass index; CVD, cardiovascular disease; DBP, diastolic blood pressure; HbA1c, haemoglobin A1C; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; Scr, serum creatinine; SUA, serum uric acid; TG, triglycerides; WC, waist circle.