Table 2.

Significantly differentially expressed genes in EZB compared with non-EZB genetic subtypes in DLBCL with MYC/BCL2 double-high expression

	Downregulated	Upregulated
Gene name	FDR 0.10: TNFRSF13B, CLECL1, PHF16, P2RX5, ERP29, SLA; FDR 0.15: PIM2, POP4, HCK, SLC5A6, PLEKHO1, STAMBPL1, ADAM8, DLGAP1-AS1, LRRC33, IL10RA, LIMD1, POU2F2, FOXP1, PARP15, DOCK10, TGIF1, IRF4	FDR 0.10: STAP1, MME, SPON1, TNKS, PTK2, CCNG2, S1PR2, ICOSLG, RRAS2, FAM208B, SWAP70, MAML3, ZFAND4, PLEKHF2, FAM134B, CDK14, PACS1, NDUFAF6, BRWD1, RASL11A, LOC101929456, RAPGEF5, LRMP, ATPIF1, SLC25A27, CPNE3, HGSNAT, DEF8, MYBL1, LOC286149, GFOD1, SSBP3, SPINK2, LHPP, MARCKSL1, PCDHGC3, WEE1, LONRF1, HIP1R, BRIP1, REL, MFHAS1, ASB13, HERC2P3, SLC30A4, STK17A, PALD1, SERPINA9, SPIRE2, PDK3, SSBP2, ENPP3, C8orf37, ITPKB, FLJ31485, SLC24A3, SEL1L3, FADS3, KIF3A, TP53INP1, CLIC4, COL14A1, ZDHHC2, ANKH, RNGTT, PQLC2, TSPAN15, CCDC85A, NAP1L3, GNA13, FNDC1, GBA3, USP34, CENPM, ITSN2, ARL14EP, VCL, LOC100131581, ARL2BP, IZUMO4, RNF8
Gene category of GO terms	GO Biological Process: "regulation of transcription\, DNA-dependent″, "regulation of transcription″, "transcription\, DNA-dependent″	GO Biological Process: "intracellular signaling cascade″ GO Molecular Function: ″kinase activity″, "transferase activity\, transferring phosphorus-containing groups″

Abbreviations: FDR, false discovery rate; GO, Gene Oncology.

Enriched Go categories were identified by Expression Analysis Systematic Explorer (EASE, A desktop version of DAVID) with EASE scores <0.05