Figure 6.

Structural and sequence comparisons. (A) Structural alignment of rMroUPO (7ZBP, orange), rCviUPO (7ZCL, yellow), and AaeUPO (2YOR, cyan). The main differences are at the long loop in AaeUPO in relation to the loop including the α3 helix in the short UPOs (green square), and the longer C-terminal tail in AaeUPO (highlighted in yellow). (B) Sequence alignment of the two short UPOs with AaeUPO. Strictly conserved residues are shown in red boxes, and red characters in white boxes specify similarity. The top and bottom lanes show the secondary structure of rMroUPO and rCviUPO, respectively, with α, β, and TT representing α helices, β sheets, and turns, respectively.