Table 2.
Results of MIC passaging in CHX or CPC summarized on a species-level.
| CHX | CPC | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Strains | MIC [µg/mL] at P1 # |
MIC [µg/mL] at P10 # |
FC P1–P10 |
Numbers of Isolates with | MIC [µg/mL] at P1 # |
MIC [µg/mL] at P10 # |
FC P1–P10 |
Numbers of Isolates with | ||
| 4-Fold | 8-Fold | 4-Fold | 8-Fold | |||||||
| MIC Increase | MIC Increase | |||||||||
|
S. anginosus n = 11 |
8 (6; 8) |
16 (16; 16) |
2 (2; 4) |
4 | 0 | 2 (2; 4) |
2 (2; 2) |
1 (0.5; 1) |
0 | 0 |
|
S. constellatus n = 1 |
4 | 4 | 1 | 0 | 0 | 1 (1; 1) |
2 (2; 2) |
2 (2; 2) |
0 | 0 |
|
S. oralis n = 24 |
8 (4; 16) |
16 (16; 16) |
2 (1; 2.5) |
6 | 0 | 2 (2; 2) |
2 (2; 2,5) |
1 (1; 1.25) |
1 | 0 |
|
S. sanguinis n = 18 |
12 (5; 28) |
16 (8; 16) |
1 (0.5; 2) |
1 | 0 | 4 (4; 4) |
2 (2; 4) |
0.5 (0.5; 1.75) |
2 | 0 |
|
S. intermedius n = 1 |
4 | 8 | 2 | 0 | 0 | 8 | 4 | 0.5 | 0 | 0 |
|
S. gordonii n = 9 |
4 (4; 8) |
16 (8; 16) |
2 (2; 4) |
4 | 0 | 2 (2; 4) |
4 (2; 4) |
1 (0.5; 2) |
0 | 0 |
|
S. salivarius n = 6 |
4 (2.5; 4) |
6 (4; 8) |
3 (1.25; 4) |
2 | 1 | 2 (2; 2) |
2 (2; 2) |
1 (1; 1) |
0 | 0 |
|
S. sobrinus n = 1 |
4 | 4 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 0 |
|
S. vestibularis n = 1 |
1 | 8 | 8 | 0 | 1 | 2 | 1 | 0.5 | 0 | 0 |
|
S. downii n = 2 |
4 (4; 4) ˟ |
16 (16; 16) ˟ |
4 (4; 4) ˟ |
2 | 0 | 3 (2; 4) ˟ |
1 (2; 2) ˟ |
0.38 (0.25; 0:5) ˟ |
0 | 0 |
|
S. parasanguinis n = 6 |
4 (4; 7) |
16 (16; 16) |
3 (2; 4) |
3 | 0 | 4 (2.5; 4) |
2 (2; 2) |
0.5 (0.5; 0.88) |
0 | 0 |
|
S. mitis n = 11 |
2 (2; 4) |
8 (4; 8) |
2 (2; 3) |
2 | 1 | 1 (1; 1) |
2 (2; 2) |
2 (1.5; 2) |
1 | 0 |
|
S. mutans n = 18 |
4 (4; 4) |
4 (4; 4) |
1 (1; 1) |
0 | 1 | 2 (2; 2) |
4 (2; 4) |
2 (1; 2) |
1 | 0 |
|
S. cristatus n = 3 |
2 (2; 3) |
4 (4; 6) |
2 (2; 2) |
0 | 0 | 1 (1; 1.5) |
4 (2.5; 4) |
2 (1.5; 3) |
1 | 0 |
|
A. naeslundii n = 7 |
1 (0.75; 2) |
2 (1.5; 2) |
2 (1; 2) |
0 | 0 | 2 (1.5; 2) |
2 (2; 2) |
1 (1; 1.5) |
0 | 0 |
|
A. oris n = 5 |
2 (1; 2) |
2 (2; 4) |
1 (1; 4) |
2 | 0 | 4 (4; 4) |
2 (2; 2) |
0.5 (0.5; 1) |
0 | 0 |
|
A. odontolyticus n = 7 |
4 (3; 4) |
4 (2; 4) |
1 (0.75; 1) |
0 | 0 | 4 (4; 4) |
2 (2; 2) |
0.5 (0.5; 0.5) |
0 | 0 |
|
R. aeria n = 7 |
2 (2; 4) |
4 (2; 4) |
1 (1; 2) |
0 | 0 | 2 (2; 4) |
2 (2; 2) |
1 (0.5; 1) |
0 | 0 |
|
R. dentocariosa n = 6 |
4 (4; 4) |
4 (4; 4) |
1 (1; 1) |
0 | 0 | 2 (2; 2) |
2 (2; 2) |
1 (1; 1) |
0 | 0 |
|
R. mucilaginosa n = 7 |
4 (3; 4) |
4 (4; 6) |
2 (1; 2) |
0 | 0 | 2 (1; 2) |
2 (2; 2) |
1 (1; 1.5) |
0 | 0 |
|
V. atypica n = 10 |
1 (1; 1) |
2 (1; 2) |
2 (1; 2) |
0 | 0 | 1 (1; 1.75) |
2 (1.25; 2) |
2 (1; 2) |
0 | 0 |
|
V. dispar n = 2 |
2 (2; 2) ˟ |
1 (1; 1) ˟ |
0.5 (0.5; 0.5) ˟ |
0 | 0 | 0.75 (0.625; 0.875) ˟ |
2 (2; 2) ˟ |
3 (2.5; 3.5) ˟ |
1 | 0 |
|
V. parvula n = 14 |
2 (1; 2) |
1.5 (1; 2) |
1 (1; 1) |
0 | 0 | 1.5 (1; 2) |
2 (2; 2) |
2 (1; 2) |
0 | 0 |
# MICs are shown on a species level as medians (1st and 3rd quartiles; for n ≥ 3), medians (minimum and maximum; for n = 2; marked by ˟) or single values (for n = 1). P1: passage 1; P10: passage 10; FC: fold-change.