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. 2022 May 19;11(5):991. doi: 10.3390/antiox11050991

Table 6.

Effect of dietary Spirulina platensis phycocyanin addition on intestinal histology.

SPC0 SPC0.25 SPC0.5 SPC0.75 SPC1 Regression #
Linear Quadratic
Duodenum
VH µm 626.55 ± 36.97 d 706.20 ± 31.64 c 921.23 ± 40.00 b 1042.44 ± 20.14 a 922.34 ± 29.14 b <0.01 <0.01
VW µm 130.36 ± 1.64 82.46 ± 35.09 115.57 ± 41.43 118.39 ± 9.57 65.51 ± 15.68 0.07 0.64
CD µm 115.26 ± 13.38 d 119.01 ± 19.78 cd 153.78 ± 24.18 b 232.42 ± 13.51 a 148.40 ± 7.78 b <0.01 <0.01
VH:CD 4.66 ± 0.44 c 5.85 ± 0.32 ab 5.81 ± 0.39 ab 5.49 ± 0.18 b 6.29 ± 0.21 a <0.01 0.02
GCC 100.70 ± 11.84 c 125.90 ± 11.64 b 139.23 ± 6.60 ab 155.59 ± 5.16 a 131.39 ± 10.24 b <0.01 <0.01
Jejunum
VH µm 854.95 ± 77.77 d 995.13 ± 66.11 c 1213.0 ± 38.47 b 1373.18 ± 104.11 a 1038.93 ± 56.37 c <0.01 <0.01
VW µm 83.30 ± 14.85 98.86 ± 8.94 95.14 ± 5.05 93.77 ± 8.11 90.82 ± 17.21 0.36 0.17
CD µm 163.78 ± 6.42 d 210.36 ± 24.55 c 254.38 ± 16.90 b 321.66 ± 17.43 a 195.31 ± 13.12 c <0.01 <0.01
VH:CD 1.28 ± 0.09 c 5.18 ± 0.93 a 4.78 ± 0.19 ab 4.27 ± 0.11 b 5.42 ± 0.18 a <0.01 <0.01
GCC 170.45 ± 17.64 c 210.36 ± 24.55 b 242.98 ± 22.74 b 298.98 ± 13.12 a 210.45 ± 11.48 b <0.01 <0.01
Ileum
VH µm 254.76 ± 44.46 c 382.31 ± 14.48 b 392.03 ± 10.37 b 506.08 ± 41.73 a 349.00 ± 28.15 b <0.01 <0.01
VW µm 72.72 ± 7.33 c 107.17 ± 5.56 ab 74.97 ± 11.78 c 91.41 ± 9.98 bc 124.69 ± 16.28 a <0.01 0.07
CD µm 86.15 ± 8.35 c 92.34 ± 4.22 bc 100.49 ± 2.51 ab 110.11 ± 10.54 a 87.73 ± 2.56 c 0.09 <0.01
VH:CD 626.55 ± 36.97 d 3.93 ± 0.22 b 3.90 ± 0.18 b 4.60 ± 0.17 a 3.98 ± 0.24 b <0.01 <0.01
GCC 130.36 ± 1.64 71.56 ± 6.23 b 80.55 ± 2.57 ab 89.01 ± 4.02 a 74.01 ± 5.14 b <0.01 <0.01

# The regressions were considered significant at p ≤ 0.05. a,b,c,d Means within the same row carrying different superscripts were significantly different (p ≤ 0.05). SPC0: control diet (basal diets with no additives); SPC0.250: basal diets supplemented with 0.250 g SPC kg1 diet; SPC0.5: basal diets supplemented with 0.5 g SPC kg1 diet; SPC0.75: basal diets supplemented with 0.75 g SPC kg1 diet; SPC1: basal diets supplemented with 1 g SPC kg1 diet. VH: villus height, VW: villus width, CD: crypt depth, and GCC: goblet cell count.