Figure 6.
The effect of arsenite on the cell sensitivity to phenylarsenicals. Various concentration of phenylarsonic acid (panel (A)) or phenylarsine oxide (panel (B)) were incubated with P. denitrificans 1222 in the absence (closed circles) or presence (open circles) of 0.5 mM arsenite. The maximum specific growth values represent means ± SD of three biological replicates. IC50 values for phenylarsonic acid were 4.26 ± 0.11 mM without arsenite and 0.54 ± 0.06 mM with arsenite, and for phenylarsine oxide were 0.42 ± 0.02 mM without arsenite and 0.44 ± 0.03 mM with arsenite.