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. 2022 May 13;12(10):1254. doi: 10.3390/ani12101254

Table 6.

Results of histopathology and endoscopic findings in 65 Helicobacter positive dogs (using a combination of diagnostic tests for Helicobacter spp. including rapid urease test, cytology, histopathology, and PCR) and 19 dogs negative for Helicobacter spp.

Helicobacter Positive Helicobacter Negative
Histopathological description
LPG + 18 (27.7%) 4 (21.1%)
LPG ++ 4 (6.2%) 2 (10.5%)
LPG +++ 1 (1.5%) 1 (5.3%)
acute purulent gastritis 2 (3.1%) -
eosinophilic gastritis - 2 (10.5%)
epithelial injury 58 (89.2%) 16 (84.2%)
fibrosis 18 (27.7%) 5 (26.3%)
lymphoid follicular hyperplasia 28 (43.1%) 3 (15.8%)
non-specific 37 (56.9%) 8 (42.1%)
neoplasia 3 (4.6%) 2 (10.5%)
(lymphoma, gastric adenocarcinoma, GI stromal tumor) (gastric adenocarcinoma, leiomyoma)
Endoscopic findings
difficult to inflate lumen 4 (6.15%) 1 (5.3%)
edema 4 (6.2%) 1 (5.3%)
erosion/ulcer 16/3 (29.2%) 2/3 (26.3%)
friability 3 (4.6%) 1 (5.3%)
granularity 29 (44.6%) 10 (52.6%)
hyperemia 5 (7.7%) 1 (5.3%)
hypertrophy 1 (1.5%) 2 (10.5%)
irregularity 1 (1.5%) 1 (5.3%)
mass 1 (1.5%) 1 (5.3%)
normal finding 22 (33.8%) 6 (31.6%)
polyp 2 (3.1%) 3 (15.8%)

Nonspecific changes-mild edema and hyperemia of lamina propria; LPG, lymphocytic-plasmacytic gastritis.