Table 1.
Groups | |||||||
---|---|---|---|---|---|---|---|
Organs | Lesions | Normal | BL | BL + BCE25 | BL + BCE50 | BL + BCE100 | BL + Lutein |
Right eye | abnormalities observed | 0/10 | 6/10 | 5/10 | 4/10 | 4/10 | 3/10 |
retinal pigmentation | 0/10 | 1/10 | 0/10 | 0/10 | 0/10 | 1/10 | |
retinal hyperemia | 0/10 | 6/10 | 5/10 | 4/10 | 4/10 | 2/10 | |
drusen | 0/10 | 3/10 | 2/10 | 2/10 | 1/10 | 1/10 | |
Left eye | abnormalities observed | 0/10 | 5/10 | 4/10 | 6/10 | 4/10 | 3/10 |
retinal pigmentation | 0/10 | 1/10 | 0/10 | 0/10 | 0/10 | 0/10 | |
retinal hyperemia | 0/10 | 5/10 | 4/10 | 4/10 | 3/10 | 2/10 | |
drusen | 0/10 | 3/10 | 2/10 | 2/10 | 1/10 | 1/10 |
Number of animals with lesions/number of animals examined. BL, blue light; BCE25, BCE 25 mg/kg; BCE50, BCE 50 mg/kg; BCE100, BCE 100 mg/kg; Lutein, lutein 4.6 mg/kg.