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. 2022 Apr 30;11(5):890. doi: 10.3390/antiox11050890

Figure 1.

Figure 1

The role of the chloride–Compound I complex (CompI-Cl−) in chlorination reactions mediated by MPO according to [44,45]. Explanations are given in the text. CompI denotes Compound I. AH2 represents a substrate that binds near the heme pocket. AHCl is the resulting chlorinated substrate.