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. 2022 Apr 30;11(5):890. doi: 10.3390/antiox11050890

Table 1.

Formation of physiologically relevant heme peroxidase-mediated brominated products.

Target Molecule Brominated Product Remarks References
Taurine
Inline graphic
Taurine bromamine
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Antimicrobial and anti-inflammatory activity [183]
Tyrosine (protein-bound)
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3-Bromotyrosine, 3,5-dibromotyrosine
Inline graphicInline graphic
EPO [122,184]
Uracil
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5-Bromouracil
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MPO [185]
2′-Deoxycytidine
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5-Bromo-2′-deoxycytidine
Inline graphic
EPO/MPO [186,187]
2′-Deoxyguanosine
Inline graphic
8-Bromo-2′-deoxyguanosine
Inline graphic
MPO [188]
Plasmalogens
(double bond adjacent to ether linkage)
Inline graphic
α-Bromo fatty aldehydes
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MPO/EPO; other products: lysophospholipids [144]