Table 3.
Evaluation of GRADEpro GDT.
| Certainty Assessment | № of Patients | Effect | Certainty | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| № of Studies | Study Design | Risk of Bias | Inconsistency | Indirectness | Imprecision | Other Considerations | Relative (95% CI |
Absolute (95% CI) |
||
| 6 | observational studies | not serious | not serious | not serious | Serious 1 | all plausible residual confounding would suggest spurious effect, while no effect was observed | 470 | HR 1.40 (1.13 to 1.75) |
2 fewer per 1.000 (From 2 fewer to 1 fewer) |
⨁⨁◯◯ Low |
1 In Wu et al. (2020), the HR value was extrapolated from the Kaplan Meier curves reported in the manuscripts; this passage is not free from error and can be a source of inaccuracy. CI, Confidence Interval; HR, Hazard Ratio.