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. 2022 Apr 21;11(5):632. doi: 10.3390/biology11050632

Table 2.

Antibiotic resistant gene prediction of Shewanella sp. N2AIL genome.

Antibiotic Class Gene/Protein Identity (%) Resistance
Mechanism
Function Location
Fluoroquinolone, Tetracycline adeF 65.03 Antibiotic efflux AdeF, a membrane fusion protein of multuidrug efflux system AdeFGH NODE_8_length_146061_cov_52.115607_51718_48584
Fluoroquinolone, Tetracycline adeF 42.43 Antibiotic efflux AdeF, a membrane fusion protein of multuidrug efflux system AdeFGH NODE_2_length_334757_cov_47.438374_143168_146326
Elfamycin EF-Tu mutants 87.53 Antibiotic target alteration Escherichia coli elongation factor Tu that confer resistance to drug class elfamycin NODE_40_length_41192_cov_51.690807_25364_24180
Fluoroquinolone, Diaminopyrimidine, phenicol
Carbapenem,
Cephalosporin, Penam
RsmA
OXA-551
86.67
97.97
Antibiotic efflux
Antibiotic inactivation
RsmA confer resistance by negatively regulating MexEF-OprN overexpression and thus virulence of P. aeruginosa.
OXA enzymes confer resistance to Carbapenem particularly in Acinetobacter baumannii
NODE_2_length_334757_cov_47.438374_217007_217204
NODE_32_length_54861_cov_49.238334_7238_6351