Table 2.
Antibiotic Class | Gene/Protein | Identity (%) | Resistance Mechanism |
Function | Location |
---|---|---|---|---|---|
Fluoroquinolone, Tetracycline | adeF | 65.03 | Antibiotic efflux | AdeF, a membrane fusion protein of multuidrug efflux system AdeFGH | NODE_8_length_146061_cov_52.115607_51718_48584 |
Fluoroquinolone, Tetracycline | adeF | 42.43 | Antibiotic efflux | AdeF, a membrane fusion protein of multuidrug efflux system AdeFGH | NODE_2_length_334757_cov_47.438374_143168_146326 |
Elfamycin | EF-Tu mutants | 87.53 | Antibiotic target alteration | Escherichia coli elongation factor Tu that confer resistance to drug class elfamycin | NODE_40_length_41192_cov_51.690807_25364_24180 |
Fluoroquinolone, Diaminopyrimidine, phenicol Carbapenem, Cephalosporin, Penam |
RsmA OXA-551 |
86.67 97.97 |
Antibiotic efflux Antibiotic inactivation |
RsmA confer resistance by negatively regulating MexEF-OprN overexpression and thus virulence of P. aeruginosa. OXA enzymes confer resistance to Carbapenem particularly in Acinetobacter baumannii |
NODE_2_length_334757_cov_47.438374_217007_217204 NODE_32_length_54861_cov_49.238334_7238_6351 |