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. 2022 May 18;11(5):682. doi: 10.3390/antibiotics11050682

Table A1.

Trends in antimicrobial use in pharmacies according to the medical institutions from which a high proportion of prescriptions were received.

Hospital Clinic
Jan-19
DPM, Median (IQR)
Jun-19
DPM, Median (IQR)
Jan-21
DPM, Median (IQR)
Jun-21
DPM, Median (IQR)
Jan-19
DPM, Median (IQR)
Jun-19
DPM, Median (IQR)
Jan-21
DPM, Median (IQR)
Jun-21
DPM, Median (IQR)
J01AA Tetracyclines 0
(0–15.6)
0
(0–19.1)
0
(0–17.9)
0
(0–21.3)
0
(0–7.0)
0
(0–7.6)
0
(0–7.7)
0
(0–9.7)
J01BA Amphenicols 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01CA Penicillins with extended spectrum 10.7
(1.6–25.6)
11.8
(1.9–26.8)
11.8
(2.8–27.2)
13.0
(2.9–25.9)
3.7
(0–14.6)
4.1
(0–16.3)
3.9
(0–14.9)
4.2
(0–13.6)
J01CE Beta-lactamase sensitive penicillins 0
(0, 0)
0
(0, 0)
0
(0, 0)
0
(0, 0)
0
(0, 0)
0
(0, 0)
0
(0, 0)
0
(0, 0)
J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 4.74
(0–10.9)
5.4
(0–12.9)
4.4
(0–13.3)
5.1
(0–13.4)
0
(0–4.3)
0
(0–5.6)
0
(0–4.3)
0
(0–4.9)
J01DB First-generation cephalosporins 0
(0–0.2)
0
(0–1.5)
0
(0–3.0)
0
(0–3.0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01DC Second-generation cephalosporins 0
(0–8.2)
0
(0–9.6)
0
(0–9.9)
1.6
(0–13.9)
0
(0–1.6)
0
(0–2.5)
0
(0–2.6)
0
(0–3.1)
J01DD Third-generation cephalosporins 33.4
(16.7–55.5)
28.9
(13.7–51.1)
20.8
(8.6–37.0)
19.2
(7.8–37.4)
40.8
(17.0–90.6)
40.0
(16.1–84.1)
25.7
(9.9–59.4)
25.1
(9.0–56.7)
J01DH Carbapenems 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01DI Other cephalosporins and penems 0
(0–1.6)
0
(0–1.4)
0
(0–0)
0
(0–1.1)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01EB Short-acting sulfonamides 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01EC Intermediate-acting sulfonamides 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01ED Long-acting sulfonamides 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01EE Combinations of sulfonamides and trimethoprim, including derivatives 4.1
(0–18.5)
4.74
(0–21.3)
3.8
(0–22.5)
2.9
(0–18.7)
0
(0–3.1)
0
(0–3.4)
0
(0–4.5)
0
(0–4.0)
J01FA Macrolides 52.0
(20.4–108.0)
47.4
(18.9–97.1)
37.9
(10.3–97.9)
36.0
(8.7–92.9)
46.3
(16.1–115.0)
39.7
(13.3–100.3)
27.3
(5.7–66.6)
23.1
(4.8–56.4)
J01FF Lincosamides 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01MA Quinolones 57.1
(27.3–96.4)
51.5
(23.9–91.2)
45.6
(18.3–82.8)
41.5
(17.4–73.2)
51.0
(18.2–111.7)
45.2
(16.0–104.8)
32.9
(10.6–74.7)
31.5
(9.5–65.0)
J01MB Other quinolones 0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
0
(0–0)
J01XX Other antibacterials 0
(0–1.6)
0
(0–2.0)
0
(0–1.0)
0
(0–1.5)
0
(0–1.9)
0
(0–2.5)
0
(0–0.7)
0
(0–1.3)

Values represent the median (interquartile range) of DPM (defined daily doses/1000 prescriptions/month).