Table 1.
Lipid composition and molar ratio of the lipids to synthesize SMLs with different types of action.
| Group | Lipid Composition | Molar Ratio | Type |
|---|---|---|---|
| A | DPPC | 1 | Non-long-circulating and thermosensitive |
| DPPC/CHEMS | 9:1 | Non-long-circulating, fusogenic, thermo- and pH-sensitive | |
| DPPC/CHEMS/DSPE-PEG | 80:15:5 | Long-circulating, fusogenic, thermo- and pH-sensitive | |
| B | DPPC/DSPC | 3:1 | Non-long-circulating and thermo-sensitive |
| DPPC/DSPC/CHEMS | 7:2:1 | Mid-long-circulating, fusogenic thermo- and pH-sensitive | |
| DPPC/DSPC/CHEMS/DSPE-PEG | 60:20:15:5 | Long-circulating, fusogenic, thermo- and pH-sensitive | |
| C | DPPC/DOPE | 7:3 | Non-long-circulating, fusogenic, pH-sensitive |
| DPPC/DOPE/CHEMS | 6:3:1 | Non-long-circulating, fusogenic, pH-sensitive | |
| DPPC/DOPE/CHEMS/DSPE-PEG | 50:30:15:5 | Long-circulating, fusogenic, pH-sensitive |