Figure 1.

Study design. Cardiac biopsies were acquired intraoperatively and 3 months after surgery. Transcriptional signatures were investigated using a microarray and further biocomputational analyses. Lastly, results were validated using immunocytochemistry. CTEPH, chronic thromboembolic pulmonary hypertension; DEGs, differentially expressed genes; GO, gene ontology; iPAH, idiopathic pulmonary arterial hypertension; LuTX, lung transplantation; PEA, pulmonary endarterectomy; RVH, right ventricular hypertrophy; TFBS, transcription factor binding site.