Table 2.
Parameter | 12–15 Years (n = 30) | 16–17 Years (n = 27) | p |
---|---|---|---|
Alcohol (g/L) | 1.64 (0.48–3.26) | 2.06 (0.51–3.06) | 0.02 * |
ALT (IU/L) | 13 (9–48) | 13 (7–38) | NS |
AST (IU/L) | 21 (14–45) | 22 (15–35) | NS |
Bilirubin (mg/dL) | 0.35 (0.15–1.49) | 0.32 (0.15–1.57) | NS |
CK (IU/L) | 218 (88–923) | 193 (79–624) | NS |
CK-MB (IU/L) | 21 (13–32) | 19 (11–55) | NS |
Urea (mg/dL) | 23 (12–35) | 21 (10–36) | NS |
PIIINP (ng/mL) | 27.74 (14,34–45.9) | 24.81 (19–48.42) | NS |
Collagen IV (ng/mL) | 73.59 (40.72–121.1) | 67.59 (50.94–120.29) | NS |
MMP-9 (ng/mL) | 69.2 (26.4–667.4) | 74.6 (39.8–355.4) | NS |
TIMP-1 (ng/mL) | 134.55 (71.1–665) | 176.1 (96.6–342.8) | 0.03 * |
MMP-9/TIMP-1 ratio | 0.57 (0.21–1) | 0.43 (0.21–1.04) | NS |
Alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK), creatine kinase-MB (CK-MB), amino terminal propeptide of type III procollagen (PIIINP), matrix metallopeptidase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1), not significant (NS), (* p < 0.05).