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. 2022 May 16;12(5):710. doi: 10.3390/biom12050710

Table 2.

Characteristics of the study group in terms of age.

Parameter 12–15 Years (n = 30) 16–17 Years (n = 27) p
Alcohol (g/L) 1.64 (0.48–3.26) 2.06 (0.51–3.06) 0.02 *
ALT (IU/L) 13 (9–48) 13 (7–38) NS
AST (IU/L) 21 (14–45) 22 (15–35) NS
Bilirubin (mg/dL) 0.35 (0.15–1.49) 0.32 (0.15–1.57) NS
CK (IU/L) 218 (88–923) 193 (79–624) NS
CK-MB (IU/L) 21 (13–32) 19 (11–55) NS
Urea (mg/dL) 23 (12–35) 21 (10–36) NS
PIIINP (ng/mL) 27.74 (14,34–45.9) 24.81 (19–48.42) NS
Collagen IV (ng/mL) 73.59 (40.72–121.1) 67.59 (50.94–120.29) NS
MMP-9 (ng/mL) 69.2 (26.4–667.4) 74.6 (39.8–355.4) NS
TIMP-1 (ng/mL) 134.55 (71.1–665) 176.1 (96.6–342.8) 0.03 *
MMP-9/TIMP-1 ratio 0.57 (0.21–1) 0.43 (0.21–1.04) NS

Alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK), creatine kinase-MB (CK-MB), amino terminal propeptide of type III procollagen (PIIINP), matrix metallopeptidase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1), not significant (NS), (* p < 0.05).