Table 4.
Independent predictors of AKD severity in patients with AKI.
| AKD Stage 1 vs. Non-AKD | AKD Stage 2 vs. Non-AKD | AKD Stage 3 vs. Non-AKD | ||||
| Adjusted OR (95% CI) | p-Value | Adjusted OR (95% CI) | p-Value | Adjusted OR (95% CI) | p-Value | |
| Age (years) | 0.981 (0.957–1.006) | 0.139 | 1.004 (0.980–1.029) | 0.741 | 1.003 (0.976–1.031) | 0.815 |
| Female | 1.155 (0.568–2.347) | 0.691 | 1.217 (0.630–2.354) | 0.559 | 1.141 (0.534–2.438) | 0.733 |
| Diabetes | 1.347 (0.603–3.008) | 0.467 | 1.375 (0.652–2.902) | 0.403 | 0.928 (0.391–2.203) | 0.865 |
| Hypertension | 0.796 (0.358–1.767) | 0.575 | 0.995 (0.475–2.087) | 0.990 | 1.094 (0.468–2.559) | 0.835 |
| CKD | 1.468 (0.518–4.158) | 0.470 | 1.449 (0.586–3.586) | 0.422 | 1.157 (0.417–3.212) | 0.779 |
| AKI KDIGO Stage 1–2 | Reference | Reference | Reference | |||
| AKI KDIGO Stage 3 | 0.368 (0.108–1.263) | 0.112 | 2.243 (0.983–5.117) | 0.055 | 6.214 (2.658–14.526) | <0.001 * |
| RRT within 0–6 Days | 1.480 (0.454–4.829) | 0.515 | 0.915 (0.276–3.037) | 0.885 | 3.366 (1.008–11.242) | 0.049 * |
| Hypovolemia | 0.130 (0.015–1.127) | 0.064 | 0.330 (0.077–1.411) | 0.135 | 0.265 (0.044–1.601) | 0.148 |
| Heart Failure | 1.477 (0.601–3.632) | 0.396 | 1.065 (0.438–2.589) | 0.889 | 0.557 (0.167–1.856) | 0.341 |
| Offending Drugs | 1.934 (0.827–4.522) | 0.128 | 2.314 (1.049–5.107) | 0.038 * | 3.132 (1.304–7.526) | 0.011 * |
| Baseline eGFR (mL/min/1.73 m2) |
0.996 (0.986–1.007) | 0.503 | 1.002 (0.994–1.010) | 0.672 | 1.004 (0.996–1.012) | 0.324 |
Age, sex, diabetes, hypertension, and covariates with a p-value of < 0.10 in univariate analyses were adjusted for multinomial logistic regression analysis with the enter method. CI, confidence interval; OR, odds ratio. *: p < 0.05.