AD | Alzheimer’s disease |
ALS | amyotrophic lateral sclerosis |
APP | amyloid precursor protein |
AQP4 | aquaporin 4 |
α-syn | α-synuclein |
BBB | blood–brain barrier |
BMP | bone morphogenetic proteins |
C3 | third complement component |
C9ORF72 | Chromosome 9 Open Reading Frame 72 |
CBD CBF |
corticobasal degeneration cerebral blood flow |
CCL | chemokine (C-C motif) ligand |
CNS | central nervous system |
CTGF | connective tissue growth factors |
CXCL | chemokine (C-X-C motif) ligand |
DA | dopaminergic |
DAT DLB |
dopamine transporter dementia with Lewy bodies |
EAE | autoimmune encephalomyelitis |
ECM | extracellular matrix |
EEG | electroencephalogram |
GABA | γ-aminobutiryc acid |
GDF | growth differentiation factors |
GFAP | glial fibrillary acidic protein |
HD HTT ICV |
Huntington’s disease huntingtin intracerebroventricular |
IFN | interferon |
IL | interleukin |
iPSC | induced pluripotent stem cell |
LPS mHTT |
Lipopolysaccharide mutant huntingtin |
MPTP | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
MS | multiple sclerosis |
MSA mTOR |
multiple system atrophy mechanistic/mammalian target of rapamycin |
NFκB | nuclear factor kappa B |
PAI-1 | plasminogen activator inhibitor-1 |
PD | Parkinson’s disease |
PSP ROS |
progressive supranuclear palsy reactive oxygen species |
SARA | Smad anchor for receptor activation |
SBE | Smad binding element |
scRNA-seq | single-cell RNA sequencing |
SMAD | Sma- and Mad-related protein |
SNpc | substantia nigra pars compacta |
snRNA-seq | single-nucleus RNA sequencing |
SOD1 | superoxide dismutase type 1 |
STAT3 | signal transducer and activator of transcription 3 |
TBI | traumatic brain injury |
TGF-β | transforming growth factor-β |
TGFBR1 | transforming growth factor-β receptor 1 |
TGFBR2 | transforming growth factor-β receptor 2 |
TLR | toll-like receptor |
TLE | temporal lobe epilepsy |
TNF | tumor necrosis factor |
TSP-1 | thrombospondin-1 |