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. 2022 May 23;10(5):1206. doi: 10.3390/biomedicines10051206
AD Alzheimer’s disease
ALS amyotrophic lateral sclerosis
APP amyloid precursor protein
AQP4 aquaporin 4
α-syn α-synuclein
BBB blood–brain barrier
BMP bone morphogenetic proteins
C3 third complement component
C9ORF72 Chromosome 9 Open Reading Frame 72
CBD
CBF
corticobasal degeneration
cerebral blood flow
CCL chemokine (C-C motif) ligand
CNS central nervous system
CTGF connective tissue growth factors
CXCL chemokine (C-X-C motif) ligand
DA dopaminergic
DAT
DLB
dopamine transporter
dementia with Lewy bodies
EAE autoimmune encephalomyelitis
ECM extracellular matrix
EEG electroencephalogram
GABA γ-aminobutiryc acid
GDF growth differentiation factors
GFAP glial fibrillary acidic protein
HD
HTT
ICV
Huntington’s disease
huntingtin
intracerebroventricular
IFN interferon
IL interleukin
iPSC induced pluripotent stem cell
LPS
mHTT
Lipopolysaccharide
mutant huntingtin
MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MS multiple sclerosis
MSA
mTOR
multiple system atrophy
mechanistic/mammalian target of rapamycin
NFκB nuclear factor kappa B
PAI-1 plasminogen activator inhibitor-1
PD Parkinson’s disease
PSP
ROS
progressive supranuclear palsy
reactive oxygen species
SARA Smad anchor for receptor activation
SBE Smad binding element
scRNA-seq single-cell RNA sequencing
SMAD Sma- and Mad-related protein
SNpc substantia nigra pars compacta
snRNA-seq single-nucleus RNA sequencing
SOD1 superoxide dismutase type 1
STAT3 signal transducer and activator of transcription 3
TBI traumatic brain injury
TGF-β transforming growth factor-β
TGFBR1 transforming growth factor-β receptor 1
TGFBR2 transforming growth factor-β receptor 2
TLR toll-like receptor
TLE temporal lobe epilepsy
TNF tumor necrosis factor
TSP-1 thrombospondin-1