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. 2022 Apr 25;12(5):636. doi: 10.3390/biom12050636

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Protein drug-based PGA prodrugs for cancer treatment. (A) Preparation of DACHPt-incorporating PEG-b-PGA polymeric micelle with cRGD ligand molecules for the targeted delivery of platinum therapeutic prodrugs to glioblastomas. Reprinted with permission from Ref. [86]. Copyright 2013, American Chemical Society. (B) Schematic illustration of the self-amplifying tumor-homing therapeutic nanoplatform working via a chain reaction mechanism. Reprinted with permission from Ref. [87]. Copyright 2020, Wiley-VCH GmbH.