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. 2022 Apr 30;10(5):1036. doi: 10.3390/biomedicines10051036

Table 2.

Categories of acute adverse reactions adapted from the ACR Manual on Contrast Media and ESUR Guideline.

Allergic-Like/Hypersensitivity Chemo-Toxic
Mild
Limited urticaria/pruritis Limited nausea/vomiting limited
Cutaneous edema Transient flushing/warmth/chills
Limited “itchy”/”scratchy” throat Headache/dizziness/anxiety/altered taste
Nasal congestion Mild hypertension
Sneezing/conjunctivitis/rhinorrhea Vasovagal reaction that resolves spontaneously
Moderate
Diffuse urticaria/pruritis Protracted nausea/vomiting
Diffuse erythema, stable vital signs Hypertensive urgency
Facial edema without dyspnea Isolated chest pain
Throat tightness or hoarseness without dyspnea Vasovagal reaction that requires and is responsive to treatment
Wheezing/bronchospasm, mild or no hypoxia
Severe
Diffuse edema, or facial edema with dyspnea Vasovagal reaction resistant to treatment
Diffuse erythema with hypotension Arrhythmia
Laryngeal edema with stridor and/or hypoxia Convulsions, seizures
Wheezing/bronchospasm, significant hypoxia Hypertensive emergency
Anaphylactic shock (hypotension + tachycardia)