Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potassium efflux drives assembly of the NLRP3 inflammasome. TWIK2 and P2X7 are potassium efflux channels that allow the flow of potassium out of the cell in response to ATP. Pore forming channels and the formation of the lysosome also induce potassium efflux. The result of this efflux induces the activation of the NLRP3 inflammasome, most likely through the activation of mitochondrial ROS. Created with BioRender.com (accessed on 17 February 2022).
