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(A). Construction of endoglin-targeted MR/optimal dual-mode molecular imaging probe using aptamer as ligand. (B). The as-synthesized nanoprobe successfully achieved MR/optimal dual modal imaging in vivo by targeting endoglin overexpressed on the surface of HCC cells and endothelial cells of neovasculature. Reproduced with permission Ref. [80]. Copyright 2018 American Chemical Society.
