Figure 1.

Heatmap and hierarchical clustering of the 62 guide DE-miRNAs. Each row represents a miRNA, and each column represents the expression changes at each time points relative to T1 (pre-smolt, one day before smoltification). T2–T4 and T5–T6 are relative expression changes during smoltification period and post-SWT period, respectively. The dendrogram and the row side colors on the left show the three major clusters of DE-miRNAs (Cluster 1-orange, Cluster 2-red, Cluster 3-green). The direction of expression changes in terms of log2 fold-change is illustrated by the color key above the heatmap. The annotation (1) indicates liver-specific miRNAs and (2) indicates some miRNAs with large changes from T1 to T4 (smoltified fish).