Skip to main content
. 2022 Apr 30;10(5):1038. doi: 10.3390/biomedicines10051038

Figure 6.

Figure 6

The therapeutic effect of the combination of 80 nM GILT and 50 uM NFKB-I on a newly diagnosed AML-FLT3 BMMNC (Patient #5) ex vivo. (A) Representative FC plots of viable CD117+CD13+ primary blasts in different treatment groups; Blue arrows (Gating) indicate further analyses of Ki-67 expression of these viable CD117+CD13+ primary blasts; (B) Cumulative FC percentage data of viable CD117+CD13+ primary blasts; (C) Cumulative FC percentage data of viable Ki-67+CD33+CD117+CD13+ primary blasts; (D) Image of partial blot films developed for proteomic analyses of cell-free supernatants from GILT-treated primary AML BMMNC cells. The black arrows indicate the control dots from the manufacturer. The yellow, red and blue arrows indicate the dots of CXCL1, CXL5 and CXCL8 respectively in the film. (E) Cumulative Mean Pixel Densities (Fold Change) of CXCL1, CXCL5, CXCL8. * p < 0.05, ** p < 0.01.