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. 2022 Apr 25;12(5):631. doi: 10.3390/biom12050631

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The PONDR^® VLXT plots and sequence peculiarities of different CoVs. Residues with the PONDR^® VLXT scores of 0.5 and above are considered disordered. (A) PONDR^® VLXT comparison of the N proteins the Wuhan-Hu-1 isolate and Omicron variant. (B) Comparison between the Wuhan-Hu-1 isolate and pangolin CoV 2017. (C) Sequence and disorder comparison of N proteins from the Wuhan-Hu-1 isolate and Omicron variant. Abbreviations: N-terminus RNA-Binding Domain (NTD RNA-Binding), Nuclear Localization Signal (NLS) [91].