Table 2.
Details of the pangolin CoVs and Bat CoVs N/M PIDs and their sequence similarities with the SARS-Co-V and SARS-CoV-2 as references. Using N-PID, SDMs have detected two sub-variants of Delta not previously detected (Delta1, Delta2).
| Coronavirus | Sequence Similarity M (%) |
M PID (%) |
Accession: UniProt (U) GenBank (G) |
Sequence Similarity N (%) |
N PID (%) |
Accession UniProt (U) GenBank (G) |
|---|---|---|---|---|---|---|
| SARS-CoV-1 Civet-SARS-CoV |
90.5 90.1 |
8.6 8.6 |
P59596(U) Q3ZTE9(U) |
90.5 90.01 |
50.2 49.1 |
P59595(U) Q3ZTE4(U) |
| Pangolin-CoV 2019 2018 2017 ** |
98.2 97.7 98.2 |
5.6 ± 0.9 a 6.3 4.5 5.9 |
QIG55948(G) QIQ54051(G) QIA48617(G) |
98 93.8 94 93.32 |
46.6 ± 1.6 a 48.7 46.3 44.9 46.5 |
QIG55953(G) QIQ54056(G) QIA48630(G) QIA48656(G) |
| SARS-CoV-2 [Wuhan-Hu-1] [Delta1] [Delta2] [Omicron] ** |
100 99.1 99.1 98.7 |
5.9 5.9 5.9 5.4 |
YP009724393(G) QUX81285(G) QUX81285(G) UFO59282(G) |
100 99.3 99.1 98.6 |
48.2 46.8 47.5 44.8 |
YP009724397(G) QYM89997(G) QYM89845(G) UFO692871(G) |
| Bat-CoV RATG13 Bat 512 HKU3 HKU4 HKU5 |
99.6 35.5 91 42.7 44.7 |
11.2 ± 15 a 4.1 15.3 7.7 16.4 11.8 |
Q9JEB4 QHR63303(G) Q0Q463(U) Q3LZX9(U) A3EXA0(U) A3EXD6(U) |
99.1 29.4 89.6 51.1 47.9 |
47.7 ± 0.9 a 48.5 46.5 48 48.5 47.1 |
QHR63308(G) Q0Q462(U) Q3LZX4(U) A3EXA1(U) A3EXD7(U) |
a Standard deviation is denoted by “±”. ** Attenuated strains detected.