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Neurotransmitter systems affected by alcohol (ethanol). Alcohol can interact with multiple neurotransmitter systems in the brain, including the serotonergic (5-HT), dopaminergic (DA), gamma-amynobutyric acid (GABA)-ergic, glutamatergic (Glu), Acetylcholinergic (ACh), and opioid systems, disrupting synaptic transmission and signalling and resulting in the dysregulation of neuronal networks that control reward, motivation, decision making, affect, and the stress response.
