Table 2.
Comparison of biochemical parameters in experimental ACI/NKyo rats (n = 5).
| Sham Control | OAT | OAT+FIR Low Intensity |
OAT+FIR High Intensity |
|||||
|---|---|---|---|---|---|---|---|---|
| baseline | 90 days | baseline | 90 days | baseline | 90 days | baseline | 90 days | |
| Body weight (g) | 256.8 ± 12.8 | 340.2 ± 9.5 | 270.8 ± 10.8 | 341.6 ± 10.7 | 258.4 ± 7.6 | 345.8 ± 4.4 | 266.2 ± 16.4 | 346.0 ± 13.5 |
| BUN (mg/dL) | 26.5 ± 1.4 | 29.6 ± 2.4 | 30.4 ± 2.4 | 29.6 ± 1.7 | 28.7 ± 3.1 | 29.7 ± 2.3 | 30.5 ± 2.9 | 33.7 ± 2.3 |
| Creatinine (mg/dL) | 0.4 ± 0.1 | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.5 ± 0.2 | 0.5 ± 0.1 | 0.6 ± 0.1 | 0.6 ± 0.2 | 0.4 ± 0.2 |
| ALT (IU/L) | 26.3 ± 1.6 | 26.0 ± 1.8 | 27.7 ± 1.8 | 28.8 ± 1.2 | 26.7 ± 1.1 | 28.0 ± 1.6 | 26.2 ± 0.9 | 26.4 ± 1.8 |
| AST (IU/L) | 34.4 ± 1.3 | 33.8 ± 1.3 | 34.4 ± 1.8 | 34.6 ± 1.4 | 33.9 ± 1.2 | 32.6 ± 1.7 | 35.2 ± 2.5 | 34.5 ± 1.7 |
| LDH (IU/L) | 786.6 ± 37.8 | 732.7 ± 20.3 | 750.8 ± 37.3 | 1166.2 ± 111.5 ab | 737.6 ± 26.6 | 1001.0 ± 142.0 ab | 757.1 ± 30.5 | 823.7 ± 57.4 c |
| HMGB1 (ng/mL) | 3.3 ± 0.7 | 3.4 ± 0.5 | 3.2 ± 0.5 | 127.5 ± 89.5 ab | 2.4 ± 0.9 | 36.5 ± 19.8 abc | 2.5 ± 0.5 | 35.0 ± 10.9 abc |
FIR, far-infrared ray; BW, body weight; OAT, orthotopic aortic transplantation; BUN, blood urea nitrogen; ALT, alanine transaminase; AST, aspartate transaminase; LDH, lactic dehydrompared. HMGB1, high mobility group box 1 protein. a p < 0.05 compared with baseline of the same group; b p < 0.05 compared with sham control ACI/NKyo (non-OAT) group at the same time point; c p < 0.05 compared with OAT (PVG/Seac to ACI/NKyo) group at the same time point.