Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 21;10(5):1194. doi: 10.3390/biomedicines10051194

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fragment of hepatitis B virus (HBV) genome analyzed in this study. It encompasses parts of the Polymerase, X (HBX), and pre-core/core open reading frames (ORF). The fragment of HBX analyzed encodes most of hepatitis B X protein (HBx) transactivating C-terminal domain, including its essential α-helical motif (Hbox) [27]. In addition, the nucleotide (nt) sequence of that fragment (nts 1596 to 1912) contains most of the core promoter sequence, including the core upstream regulatory sequence (CURS) and the basic core promoter (BCP) with the TATA-like boxes 1–4 (TA1–TA4); nt positions are shown as described in [6]. It also includes the Enhancer II and the direct repeat 1 (DR1) sequences; nt positions are shown as described in [7].