Table 1.
Main demographic, clinical, and echocardiographic characteristics of the studied Hungarian index HCM patients (n = 242). Data are expressed as mean value ± SD or number (%) of patients. * In patients with a resting gradient >50 mmHg. Abbreviations: HCM: hypertrophic cardiomyopathy; ICD: implantable cardioverter defibrillator; LV: left ventricular; LVOTG: left ventricular outflow tract gradient; PTSMA: percutaneous transluminal septal myocardial ablation.
| Demographics | |
| Males: | 127 (52%) |
| Age at diagnosis (years): | 44 ± 11 |
| Follow up (years): | 12 ± 9 |
| Familial disease (proven): | 62 (25.5%) |
| Echocardiography data | |
| Left atrial diameter (mm): | 46 ± 10 |
| Maximal LV wall thickness (mm): | 23 ± 7 |
| LV end-diastolic diameter (mm): | 44 ± 13 |
| LV end-systolic diameter (mm): | 26 ± 11 |
| LV ejection fraction (%): | 68 ± 13 |
| LVOTG rest ≥ 50 mm Hg: | 49 (20%) |
| LVOTG rest (mmHg) *: | 74 ± 36 Hgmm |
| LVOTG Valsalva (mmHg) *: | 93 ± 48 Hgmm |
| Treatment, device, and intervention | |
| Medical treatment: | |
| Beta blocker: | 230 (95%) |
| Verapamil: | 17 (7%) |
| Disopyramide: | 50 (20%) |
| Amiodarone: | 41 (17%) |
| ICD implantation: | 46 (19%) |
| Septal reduction therapy (PTSMA or myectomy): | 32 (13%) |
| Follow up: | |
| Death during follow up: | 43 (18%) |
| Age at death (years): | 52 ± 12 |
| Death after diagnosis (years): | 10 ± 7 |
| HCM-related death: | 32 (75%) |
| Cause of death: | |
| Heart failure: | 10 (25%) |
| Sudden cardiac death: | 12 (28%) |
| Thromboembolism: | 6 (13%) |
| Other: | 4 (9%) |