Table 1.

Demographic characteristics and biological data for normal controls and depressed patients with DSM-5 suicidal behavior disorder classified according to specifiers: current or in early remission.

	Control Subjects (n = 18)	SBD-REM (n = 16)	SBD-CUR (n = 14)
Age, years a	37.8 ± 7.8	36.9 ± 11.4	33.0 ± 6.9
Gender	9 M/9 F	5 M/11 F	7 M/7 F
HAM-D	…	26.4 ± 4.5	28.0 ± 4.3
Melancholic features (n)	…	4	4
TSA, months	…	17.2 ± 3.1	3.9 ± 3.2 †††
NSA	…	1.4 ± 0.6	1.3 ± 0.6
8 AM and 11 PM TRH tests
8 AM-FT4BL, pmol/L	13.6 ± 1.5	14.5 ± 3.0	12.3 ± 2.1 *
8 AM-FT3BL, pmol/L	5.1 ± 0.4	5.5 ± 0.7	5.3 ± 0.8
8 AM-TSHBL, mU/L	1.23 ± 0.44	1.42 ± 0.69	1.10 ± 0.38
8 AM-∆TSH, mU/L	9.32 ± 4.41	8.83 ± 3.61	7.30 ± 3.60
11 PM-TSHBL, mU/L	1.33 ± 0.75	1.12 ± 0.52	0.75 ± 0.29 *
11 PM-∆TSH, mU/L	13.66 ± 4.94	12.35 ± 3.67	9.00 ± 3.93 **†
∆∆TSH, mU/L	4.31 ± 1.16	3.54 ± 1.63	1.67 ± 2.55 ***†
Apomorphine test
ACTHBL (ng/L)	23.0 ± 17.1	20.0 ± 8.6	30.9 ± 19.9
∆ACTH (ng/L)	24.8 ± 30.1	19.2 ± 22.7	44.1 ± 38.2 *†
CORBL (nmol/L)	282 ± 110	321 ±114	251 ± 77
∆COR (nmol/L)	176 ± 181	111 ± 131	167 ± 124
GHBL (µg/L)	0.6 ± 0.3	0.7 ± 0.3	0.7 ± 0.4
∆GH (µg/L)	12.0 ± 7.4	8.9 ± 8.3	21.0 ± 13.0 *†††
Maximum post-DST
COR, nmol/L	44 ± 56	85 ± 103	66 ± 62

^a Values are mean ± SD. SBD, suicidal behavior disorder; CUR, current; REM, early remission; HAM-D, 17-item Hamilton Rating Scale for Depression; TSA, time elapsed between the last suicide attempt and the investigation; NSA, number of suicide attempts; FT4, free thyroxine; T3, free triiodothyronine; TSH, thyrotropin; ACTH, adrenocorticotropin hormone; COR, cortisol; GH, growth hormone; BL, basal concentration; ∆, peak concentration minus basal concentration; ∆∆TSH, 2300h-∆TSH minus 0800h-∆TSH; DST, dexamethasone suppression test. Comparisons between control and depressed groups, * p ≤ 0.05; ** p≤ 0.01; *** p ≤ 0.005; comparisons between SBD-REM and SBD-CUR groups, † p ≤ 0.05; ††† p ≤ 0.005 (by U-test).