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Effectiveness of T-DM1 in patients who initiated T-DM1 in any treatment line. (A) TTNT or death; (B) TTLA of T-DM1 before discontinuation or death; (C) rwPFS; and (D) OS.CI = confidence interval; NE = not estimable; No = number; OS = overall survival; rwPFS = real-world progression-free survival; T-DM1 = trastuzumab emtansine; TTLA = time to last administration; TTNT = time to next relevant treatment.
