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. 2022 May 20;11(10):1706. doi: 10.3390/cells11101706

Figure 1.

Figure 1

Exercise upregulated circulating BCAA levels in humans. (A). The clustering of orthogonal projection to latent structures-discriminant analysis (OPLS-DA) in positive (left panel) and negative (right panel) ion mode. (B). Heat map of the differentially concentrated metabolites in plasma from trained and untrained subjects. (C). The KEGG pathways involved in the differentially concentrated metabolites. (D). Pathway enrichment analysis indicated that both BCAA degradation and biosynthesis were changed obviously. (E). Heat map of all detected BCAAs. (F). Circulating BCAA concentrations in trained and untrained subjects. Values are presented as mean ± SEM. n = 16 subjects for each group. * p < 0.05; *** p < 0.001.