Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A possible scheme for multi-targeting PDAC to prevent/reverse chemoresistance. A rational association of drugs will probably enhance gemcitabine anti-cancer effects and reduce resistance. The drugs proposed to be associated with gemcitabine have low or no toxicity at all and would not represent an extra burden for the patient. Furthermore, amiloride and tocilizumab may prevent cancer cachexia [603,604], a frequent occurrence in PDAC.
