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. 2022 May 18;14(10):2486. doi: 10.3390/cancers14102486

Table 2.

Activity of metabolic intermediaries of gemcitabine.

Gemcitabine (Difluoro Deoxycytidine) Inactive
Gemcitabine (Difluoro Deoxycytidine Monophosphate) Inactive
Gemcitabine (Difluoro Deoxycytidine DiphosphateI) Inhibits RR
Gemcitabine (Difluoro Deoxycytidine Triphosphate) Inhibits DNA synthesis