Table 2.
Resistance profiles of Gram-negative bacteria isolated from positive urine and blood cultures towards a set of commonly used antibiotics in neonatal intensive care unit (NICU).
| - | Number of Isolates | Amikacin | Ampicillin | Cefepime | Cefoxitin | Ciprofloxacin | Gentamicin | Imipenem | Nitrofurantoin | Meropenem | Piperacillin | Tigecycline | Trimethoprim/Sulfamethoxazole |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Urine isolates | |||||||||||||
| Escherichia coli | 21 | 4 (19) | 0 | 3 (14) | 0 | 7 (33) | 7 (33) | 4 (19) | 5 (24) | 3 (14) | 9 (43) | 6 (29) | 13 (62) |
| Klebsiella pneumoniae | 17 | 7 (41) | 1 (6) | 0 | 0 | 2 (12) | 7 (41) | 0 | 2 (12) | 0 | 3 (18) | 2 (12) | 3 (18) |
| Klebsiella pneumoniae ESBL * | 7 | 4 (57) | 5 (71) | 6 (86) | 1 (14) | 3 (43) | 5 (71) | 0 | 1 (14) | 0 | 1 (14) | 0 | 1 (14) |
| Pseudomonas aeruginosa | 3 | 2 (67) | 2 (67) | 0 | 1 (33) | 1 (33) | 2 (67) | 0 | 2 (67) | 0 | 0 | 2 (67) | 3 (100) |
| Blood isolates | |||||||||||||
| Klebsiella pneumoniae ESBL * | 2 | 1 (50) | 1 (50) | 2 (100) | 1 (50) | 0 | 1 (50) | 0 | 0 | 0 | 0 | 0 | 0 |
| Pseudomonas aeruginosa ESBL * | 1 | 0 | 1 (100) | 1 (100) | 1 (100) | 1 (100) | 1 (100) | 1 (100) | 0 | 1 (100) | 0 | 0 | 1 (100) |
| Acinetobacter baumannii | 3 | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 0 | 3 (100) |
Data are presented as the total number of resistant isolates during the study period. Numbers in brackets are percentages. * Isolates resistant to ceftazidime (third generation cephalosporin) are considered as extended-spectrum β-lactamase producing. Resistance profile of bacterial isolate present in both urine and blood was included among urine isolates only.